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Overview

The medicinal chemistry team within the Center for Drug Discovery supports client needs by conducting hit-to-lead and lead optimization. We integrate medicinal chemistry into larger projects focused on drug discovery and development, including computational chemistry, in vitro assay development and HTS screening, in vivo behavioral pharmacology, ADME/PK bioanalytics, and regulatory support.

We have an immediate need for a Medicinal Chemist with experience in peptide synthesis to join an exciting and growing team.  Ideally, you will be a highly-motivated and organized individual who desires a role involved in the synthesis of peptides and small molecules as ligands for various biological targets including kinases, G protein-coupled receptors, ion channels, and antimicrobial targets.

At RTI, you will be provided the opportunity to conduct meaningful work in a collaborative, cross functional environment.  We are focused on your career development and provide a generous benefits packages that includes tuition reimbursement, parental leave, paid time off, medical/dental, and 401K.

Responsibilities

• Assist with experimental design
• Perform compound synthesis independently or as a member of a team
• Ensure proper execution of studies and record-keeping
• Perform data analyses and prepare manuscripts for publication
• Attend conferences to present novel research findings
• Assist with grant applications
• Train junior investigators and technicians as needed
• Review literature and patents to retrieve scientific information
• Other duties as assigned by PI

Qualifications

• Ph.D. in synthetic or medicinal chemistry or a related discipline field of study
• Experience with a wide variety of chemical reactions
• Experience with peptide and nucleotide chemistry
• Experience with in vitro assays for antibacterial activity
• Experience with LC/MS, NMR and chiral separation techniques
• Experience with cell cultures and/or biological assays is highly desired
• Knowledge of basic computational techniques is highly desired
• Must be able to work independently in a fast-paced environment

EEO & Pay Equity Statements

For San Francisco, CA USA Job Postings Only: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Further information is available here.

The anticipated pay range for this role is listed below. Our pay ranges represent national averages and may vary by location as a geographic differential may be applied to some locations within the United States.

RTI considers multiple factors when making an offer including, for example: established salary range, internal budget, business needs, and education and years of work experience possessed by the applicant. Further, salary is merely one element to our offer.

At RTI, we demonstrate our commitment to rewarding individual and team achievement through a total rewards package. This package includes (among other things) a competitive base salary, a generous paid time off policy, merit based annual increases, bonus opportunities and a robust recognition program. Other benefits include a competitive range of insurance plans (including health, dental, life, and short-term and long-term disability), access to a retirement savings program such as a 401(k) plan, paid parental leave for all parents, financial assistance with adoption expenses or infertility treatments, financial reimbursement for education and developmental opportunities, an employee assistance program, and numerous other offerings to support a healthy work-life balance.

Hiring Salary Range