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Thermo Fisher Scientific
Thermo Fisher Scientific

Production Scientist I, Antibody

location Rockford, Illinois

Job Type Full Time

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Job Description

Position Summary:

A manufacturing laboratory position in an ISO certified environment supporting Thermo Fisher Scientific Immunoassay Systems product line.  The associate should have exposure and understanding through either reading or preferably hands on experience in such biochemical lab techniques as listed below:

Key Responsibilities: 

  • Understand and follow:
    • Safe lab practices
    • Good documentation practices.  The associate is expected to maintain detailed documentation and implement updates in support of ISO requirements
  • Commit to producing and maintaining the highest standard of quality in antibody production
  • Ensure on-time delivery of production work and projects
  • Perform with assistance of batch records, standard work instructions, operating procedures or shadowing with a trained associate:
    • Protein isolation and purification
    • Chromatography (affinity, ion exchange, size exclusion).  FPLC experience helpful
    • Protein modification (cross linking, fluorescent, protein and small molecule conjugations)
    • Protein lyophilization
    • Carrier protein conjugations with peptides or fusion proteins
    • Antibody purification / modification experience
    • Antibody validation via various functional tests, i.e. WB / ELISA / IHC / IP / IF / FACS
    • SDS-PAGE
    • Small and large scale buffer preparations
    • Protein/enzyme assays
    • UV / VIS Spectrophotometry measurements
    • Set up and take down of labware
  • Maintain accurate inventory
    • Assist the manufacturing support associate and/or material handling in cycle counting or physical inventory as required

Minimum Requirements/Qualifications:

  • Minimum of a Bachelors of Science degree in a Biochemical / Biological sciences, Chemistry, or Life science emphasis;  Masters degree, preferred 
  • Demonstrate 0 to 2 years experience.  It is desired that the associate have prior experience in a manufacturing role with a solid understanding relevant to corporate goals, objectives and strategies
  • Demonstrate general hands on lab skills as would be acquired in a 4 year Bachelors level science degree.  Experience in organic chemistry is helpful
  • Able to demonstrate analytical thought process and understand experimental design when explained 
  • Experience with aseptic handling technique.  Autoclave experience is helpful.
  • Ability to lift 50 pounds
  • Understanding of molar theory
  • Exposure to working with animal and human blood, cells, sera and tissues
  • Hazardous Waste Generation/Management: Associates in this position may as part of their job activities generate or manage hazardous waste as defined by the Illinois Environmental Protection Agency.  Individuals in this position are required to receive initial hazardous waste training within the first 30 working days of assignment.  The initial waste training shall include but not be limited to the following general categories:  Identifying hazardous and solid waste, hazardous waste management, recycling, treatment and disposal, emergency preparedness, record keeping, pollution prevention and waste reduction.  Following initial training the Associate in this position will receive annual refresher training in the same topic field as listed above.  Associate should be comfortable working frequently with organics, including flammable solvents, strong acids / bases, potential biohazards (including raw animal serums), large scale bacterial cultures, and hazardous chemicals

This position has not been approved for Relocation Assistance.